Description

Glemanserin CAS NO 132553-86-7 is a high-purity pharmaceutical intermediate and research chemical of significant interest in neuropharmacology. This compound is valued for its role in the development and synthesis of novel therapeutic agents targeting specific serotonin receptor pathways. It is primarily utilized by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and academic research institutions engaged in central nervous system (CNS) drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of advanced active pharmaceutical ingredients (APIs) for neurological research.
• Neuropharmacology Research: Used as a reference standard and precursor in studies targeting serotonin (5-HT) receptor subtypes for potential therapeutic applications.
• Process Development: Employed in the scale-up and optimization of synthetic routes for candidate drugs within medicinal chemistry programs.
• Contract Manufacturing: Supplied to CMOs and CDMOs for the production of non-commercial batches for clinical trials and preclinical studies.
• Academic & Institutional Research: Serves as a critical reagent in university and government labs investigating CNS disorders and receptor mechanisms.
• Analytical Standard: Provides a high-purity standard for method development and quality control in analytical laboratories (HPLC, LC-MS).

Basic Information

Product Name	Glemanserin
CAS No.	132553-86-7
Molecular Formula	C19H21FN2O2
Molecular Weight	328.38 g/mol
Synonyms	Glemanserin; DU-125530; N-[2-[4-(5-Fluoro-1H-indol-3-yl)piperidin-1-yl]ethyl]acetamide; 1-[2-(Acetylamino)ethyl]-4-(5-fluoro-1H-indol-3-yl)piperidine; DU125530; DU 125530
EINECS	Contact for details

Quality Control

Our Glemanserin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot undergoes comprehensive analytical testing, including identification (IR, NMR), purity assay (HPLC), and control of specified impurities. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.