Description

1H-Indene, 5-Ethynyl-2,3-Dihydro- CAS NO 132464-86-9 is a high-purity, advanced pharmaceutical intermediate characterized by its unique indene core functionalized with an ethynyl group. This compound is of significant commercial value as a critical building block in the synthesis of complex organic molecules, particularly in medicinal chemistry and materials science. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging its reactive ethynyl group for structural diversification.
• Organic Light-Emitting Diodes (OLEDs): Serves as a core structure or a functionalization point in the synthesis of novel electron-transport or emissive materials for display technologies.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create specialized ligands for catalytic processes, including cross-coupling reactions.
• Academic & Industrial Research: A valuable reagent for synthetic organic chemists exploring new reaction methodologies and constructing complex molecular architectures.
• Polymer and Material Science: Acts as a monomer or cross-linking agent for developing specialty polymers with tailored thermal or electronic properties.

Basic Information

Product Name	1H-Indene, 5-Ethynyl-2,3-Dihydro-
CAS No.	132464-86-9
Molecular Formula	C11H8
Molecular Weight	140.18 g/mol
Synonyms	5-Ethynyl-2,3-dihydro-1H-indene; 5-Ethynylindane; 2,3-Dihydro-5-ethynyl-1H-indene; 5-Ethynylindan; 132464-86-9; 5-Ethynyl-2,3-dihydroindene; 5-Ethynylindan-1-one (precursor related); Ethynylindane
EINECS	Contact for details

Quality Control

Our 1H-Indene, 5-Ethynyl-2,3-Dihydro- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider storing under an inert atmosphere (e.g., nitrogen or argon) to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.