Description

Metronidazole Myristate is a pharmaceutical-grade ester derivative of the widely used nitroimidazole antibiotic, metronidazole. This compound is specifically engineered to enhance the lipophilicity and stability of the parent drug, making it a critical intermediate for advanced pharmaceutical formulations. It is primarily utilized by manufacturers in the pharmaceutical and veterinary medicine industries for developing prodrugs and controlled-release dosage forms, particularly for topical and transdermal applications.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of lipophilic prodrugs of metronidazole, improving drug delivery and bioavailability.
• Topical Formulations: Used in the development of creams, ointments, and gels for the treatment of dermatological infections, including rosacea and other anaerobic bacterial conditions.
• Veterinary Medicine: Incorporated into long-acting injectable or topical preparations for treating protozoal and anaerobic bacterial infections in animals.
• Cosmeceutical Research: Investigated for use in specialized skincare products targeting microbiome-related skin issues due to its antimicrobial properties.
• Controlled-Release Drug Delivery Systems: Serves as a modified active pharmaceutical ingredient (API) in the design of sustained-release implants or patches.
• Chemical Synthesis Reference Standard: Used as a high-purity standard in analytical laboratories for quality control and method development.

Basic Information

Product Name	Metronidazole Myristate
CAS No.	132367-97-6
Molecular Formula	C21H39N3O4
Molecular Weight	397.56 g/mol
Synonyms	Metronidazole Myristate Ester; 2-Methyl-5-nitro-1H-imidazole-1-ethanol tetradecanoate; Metronidazole Tetradecanoate; Metronidazole 1-Tetradecanoyl Ester; Myristic Acid Metronidazole Ester; 1-(2-Hydroxyethyl)-2-methyl-5-nitroimidazole Myristate; MNZ-MYR
EINECS	Contact for details

Quality Control

Our Metronidazole Myristate is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) is provided, detailing parameters such as identity, assay, purity, and related substances. We adhere to cGMP principles, and our quality protocols are designed to support regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.