Description

1-o-Hexadecyl-2-Eicosapentaenoyl-Sn-Glycero-3-Phosphocholine is a specialized, semi-synthetic phospholipid derivative, also known as a plasmalogen analogue, designed for advanced research and formulation applications. This compound is critical for studying membrane biophysics, lipid signaling, and for developing targeted drug delivery systems due to its unique structural features. It is primarily utilized by researchers and product developers in the pharmaceutical, nutraceutical, and advanced biomaterials sectors.

Application

• Lipidomics and Biomedical Research: As a critical standard and reagent for studying the role of plasmalogens and polyunsaturated fatty acids (PUFAs) in cell membrane dynamics, signaling, and neurological health.
• Drug Delivery System Development: A key component in the formulation of liposomes, lipid nanoparticles (LNPs), and other nanocarriers for targeted therapeutic delivery, leveraging its membrane-fusogenic properties.
• Nutraceutical and Cosmeceutical Formulations: Incorporated into high-end supplements and topical products for its potential bioactive benefits related to the eicosapentaenoic acid (EPA) moiety.
• Biomembrane Model Systems: Used to create more physiologically relevant artificial membranes (e.g., liposomes, supported lipid bilayers) for biophysical and permeability studies.
• Reference Standard for Analytical Chemistry: Serves as a high-purity qualitative and quantitative standard in HPLC, LC-MS, and other analytical methods for lipid analysis.

Basic Information

Product Name	1-o-Hexadecyl-2-Eicosapentaenoyl-Sn-Glycero-3-Phosphocholine
CAS No.	132196-28-2
Molecular Formula	C44H84NO8P
Molecular Weight	786.11 g/mol
Synonyms	1-O-Hexadecyl-2-(5Z,8Z,11Z,14Z,17Z-eicosapentaenoyl)-sn-glycero-3-phosphocholine; C16:0 plasmenyl-EPA PC; 1-O-Hexadecyl-2-eicosapentaenoyl-sn-glycero-3-phosphocholine; Plasmalogen PC (16:0p/20:5); sn-Glycero-3-phosphocholine, 1-O-hexadecyl-2-(5Z,8Z,11Z,14Z,17Z-eicosapentaenoyl)-; EPA Plasmenylcholine; 1-(1Z-Hexadecenyl)-2-eicosapentaenoyl-sn-glycero-3-phosphocholine (plasmalogen form)
EINECS	Contact for details

Quality Control

Our 1-o-Hexadecyl-2-Eicosapentaenoyl-Sn-Glycero-3-Phosphocholine is produced under strict quality management systems. Each batch undergoes comprehensive analytical characterization using techniques including NMR, HPLC, and mass spectrometry to confirm identity, purity, and lipid composition. Certificates of Analysis (COA) detailing batch-specific results are provided to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white waxy solid or oil
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Assay (Phosphorus)	≥ 98% (of theoretical)
Solvent Content (Residual)	< 2% (by NMR or GC)
Peroxide Value	< 2.0 meq/kg
Water Content (KF)	< 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.