Description

Dl-Phenylalanine, 4-Bromo-n-[(1,1-Dimethylethoxy)Carbonyl]- CAS NO 132153-48-1 is a protected amino acid derivative, specifically a Boc-protected bromo-phenylalanine, which serves as a critical chiral building block in advanced organic synthesis. This compound is essential for the controlled introduction of a brominated phenylalanine moiety, enabling precise structural modifications in target molecules. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of peptide-based therapeutics, enzyme inhibitors, and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for peptide and peptidomimetic drugs.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate a bromine-functionalized phenylalanine residue, allowing for further site-specific derivatization via cross-coupling reactions.
• Chemical Biology & Proteomics: Serves as a building block for synthesizing activity-based probes, enzyme substrates, or inhibitors to study protein function and interactions.
• Agrochemical Research: Employed in the synthesis of advanced crop protection agents and herbicides that require specific chiral amino acid structures.
• Material Science: Potential use in the synthesis of specialized polymers or dendrimers with tailored functional properties.

Basic Information

Product Name	Dl-Phenylalanine, 4-Bromo-n-[(1,1-Dimethylethoxy)Carbonyl]-
CAS No.	132153-48-1
Molecular Formula	C14H18BrNO4
Molecular Weight	344.20 g/mol
Synonyms	Boc-4-Bromo-DL-phenylalanine; N-(tert-Butoxycarbonyl)-4-bromo-DL-phenylalanine; 4-Bromo-DL-phenylalanine N-Boc derivative; tert-Butyl (4-bromophenyl)alaninate; (RS)-2-[(tert-Butoxycarbonyl)amino]-3-(4-bromophenyl)propanoic acid; 4-Br-DL-Phe(Boc)-OH; Boc-4-Br-DL-Phe-OH
EINECS	Contact for details

Quality Control

Our Dl-Phenylalanine, 4-Bromo-n-[(1,1-Dimethylethoxy)Carbonyl]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis, NMR, and MS for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	DL-mixture (Racemic)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.