Description

4-Deoxy-4-Fluoromuscarine is a fluorinated analog of the classic muscarinic acetylcholine receptor agonist, muscarine. This compound is of significant interest in neuroscience and pharmacology research as a selective tool for probing muscarinic receptor subtypes and studying cholinergic signaling pathways. It is primarily utilized by pharmaceutical R&D departments, academic research institutions, and biotechnology companies focused on neuropharmacology and drug discovery.

Application

• Neuroscience Research: A key pharmacological tool for studying the function and distribution of muscarinic acetylcholine receptor (mAChR) subtypes in the central and peripheral nervous systems.
• Drug Discovery & Development: Serves as a reference compound and a structural template for the design and screening of new therapeutics targeting neurological disorders such as Alzheimer's disease, Parkinson's disease, and schizophrenia.
• Biochemical Assays: Used in in vitro binding assays and functional studies (e.g., calcium mobilization, GTPγS binding) to characterize receptor-ligand interactions and signal transduction mechanisms.
• Academic & Clinical Research: Employed in university and hospital laboratories to investigate the role of the cholinergic system in learning, memory, smooth muscle contraction, and cardiac function.
• Toxicology Studies: Acts as a precise agent for modeling cholinergic toxicity and understanding the effects of muscarinic receptor overstimulation or blockade.

Basic Information

Product Name	4-Deoxy-4-Fluoromuscarine
CAS No.	132113-37-2
Molecular Formula	C9H18FNO2+
Molecular Weight	191.25 g/mol (cation)
Synonyms	4-Fluoro-4-deoxymuscarine; (2S,4R,5S)-4-Fluoro-1-methyl-2-(2-oxoethyl)-1,3-oxathiolan-5-aminium; 4-Fluoromuscarine; Fluoromuscarine; Muscarine, 4-deoxy-4-fluoro-; 4-Fluoro-deoxymuscarine
EINECS	Contact for details

Quality Control

Our 4-Deoxy-4-Fluoromuscarine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, essential for reliable research data. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We support research standards compliance and can provide material for method validation upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.