Description

(1R,2R)-Bis[(2-Methoxyphenyl)Phenylphosphino]Ethane Diborane is a chiral, bidentate phosphine ligand complexed with diborane, widely recognized for its role in asymmetric catalysis. This compound matters because it provides exceptional stereoselectivity and reactivity in critical transition-metal-catalyzed reactions, enabling the production of high-value, enantiomerically pure intermediates. It is primarily needed by research institutions and pharmaceutical manufacturers developing novel active pharmaceutical ingredients (APIs) and advanced fine chemicals.

Application

• Asymmetric Hydrogenation: A key ligand for the enantioselective reduction of prochiral olefins, ketones, and imines in pharmaceutical synthesis.
• Cross-Coupling Catalysis: Employed in asymmetric C-C and C-X bond-forming reactions to construct complex chiral molecules.
• Pharmaceutical Intermediate Synthesis: Critical for the production of enantiomerically pure building blocks for APIs in oncology, neurology, and cardiology.
• Agrochemical Research: Used in the development of chiral pesticides and herbicides with improved efficacy and environmental profiles.
• Academic & Industrial R&D: A valuable tool for methodology development in organic synthesis and catalysis research.
• Fine Chemical Manufacturing: Facilitates the scalable production of specialty flavors, fragrances, and advanced materials.

Basic Information

Product Name	(1R,2R)-Bis[(2-Methoxyphenyl)Phenylphosphino]Ethane Diborane
CAS No.	131830-91-6
Molecular Formula	C30H32B2O2P2
Molecular Weight	508.94 g/mol
Synonyms	(R,R)-DIPAMP·BH3; (1R,2R)-(-)-1,2-Bis[(2-methoxyphenyl)phenylphosphino]ethane-borane; (R,R)-(-)-1,2-Bis(o-anisylphenylphosphino)ethane diborane adduct; (R,R)-DIPAMP-Borane Complex; (1R,2R)-Bis(o-methoxyphenylphenylphosphino)ethane diborane; (R,R)-Bis(2-methoxyphenylphenylphosphino)ethane diborane; (R,R)-DIPAMP·2BH3; (-)-DIPAMP·BH3 Complex
EINECS	Contact for details

Quality Control

Our (1R,2R)-Bis[(2-Methoxyphenyl)Phenylphosphino]Ethane Diborane is manufactured under strict quality systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC and NMR spectroscopy, to verify identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to maintain stability and prevent oxidation. The container should be kept in a cool, dry, and well-ventilated area, separate from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (ee)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.