Description

1,4-Bis(Chloromethyl)Tetrafluorobenzene is a versatile fluorinated aromatic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring two reactive chloromethyl groups on a tetrafluorobenzene core, makes it a critical precursor for constructing complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors seeking to incorporate fluorinated aromatic systems.

Application

• Pharmaceutical Intermediate: Serves as a key synthon for the development of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic motifs to enhance metabolic stability, bioavailability, and membrane permeability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the introduction of fluorine atoms can improve efficacy, selectivity, and environmental profile.
• Liquid Crystal & OLED Materials: Acts as a fundamental building block for fluorinated mesogens and electron-transport materials used in display technologies and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modification: Employed to synthesize fluorinated monomers and cross-linking agents for high-performance polymers, coatings, and resins with enhanced chemical, thermal, and surface properties.
• Ligand & Catalyst Preparation: Useful for preparing sophisticated fluorinated ligands for catalysis and metal-organic frameworks (MOFs), enabling novel reaction pathways and separation processes.
• Custom Synthesis & R&D: A valuable starting material in research and development for creating novel fluorinated compounds across various chemical disciplines.

Basic Information

Product Name	1,4-Bis(Chloromethyl)Tetrafluorobenzene
CAS No.	131803-37-7
Molecular Formula	C8H4Cl2F4
Molecular Weight	259.02 g/mol
Synonyms	1,4-Bis(chloromethyl)-2,3,5,6-tetrafluorobenzene; 2,3,5,6-Tetrafluoro-1,4-bis(chloromethyl)benzene; p-Bis(chloromethyl)tetrafluorobenzene; α,α'-Dichloro-2,3,5,6-tetrafluoro-p-xylene; Tetrafluoro-p-xylylene dichloride; 1,4-Bis(chlorodifluoromethyl)benzene (common misnomer); 1,4-Di(chloromethyl)-2,3,5,6-tetrafluorobenzene; p-Xylylene dichloride, tetrafluoro-
EINECS	Contact for details

Quality Control

Our 1,4-Bis(Chloromethyl)Tetrafluorobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.