Description

n-[(1,1-Dimethylethoxy)Carbonyl]-L-Alanyl-n-Methyl-D-Tryptophan Methyl Ester is a sophisticated, non-natural dipeptide building block designed for advanced pharmaceutical research and development. This compound is critical for medicinal chemists working on peptide-based therapeutics, where it serves as a key intermediate for introducing specific conformational and functional properties. It is primarily utilized in the synthesis of novel drug candidates targeting complex diseases, offering researchers precise control over molecular structure and bioactivity.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore and optimize the biological activity of peptide analogs.
• Protease Inhibitor Development: Serves as a core component in the design and synthesis of selective enzyme inhibitors.
• Peptide Library Synthesis: Employed in combinatorial chemistry for generating diverse peptide libraries for high-throughput screening.
• Bioconjugation & Labeling: Acts as a starting material for creating labeled peptides or peptide-drug conjugates for diagnostic and therapeutic applications.
• Academic & Institutional R&D: Supports fundamental research in biochemistry, pharmacology, and organic synthesis at universities and research institutes.

Basic Information

Product Name	n-[(1,1-Dimethylethoxy)Carbonyl]-L-Alanyl-n-Methyl-D-Tryptophan Methyl Ester
CAS No.	131791-78-1
Molecular Formula	C22H29N3O5
Molecular Weight	415.48 g/mol
Synonyms	Boc-L-Ala-N-Me-D-Trp-OMe; Boc-L-Alanyl-N-methyl-D-tryptophan methyl ester; (2S)-2-[[(2R)-1-Methoxy-3-(1H-indol-3-yl)-1-oxopropan-2-yl](methyl)amino]-N-(tert-butoxycarbonyl)propanamide; N-(tert-Butoxycarbonyl)-L-alanyl-N-methyl-D-tryptophan methyl ester; N-Boc-L-Ala-N-Me-D-Trp-OMe; Boc-Ala-N-Me-D-Trp-OMe; L-Alanine, N-[(1,1-dimethylethoxy)carbonyl]-, N-methyl-D-tryptophan methyl ester
EINECS	Contact for details

Quality Control

Our n-[(1,1-Dimethylethoxy)Carbonyl]-L-Alanyl-n-Methyl-D-Tryptophan Methyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and comprehensive identification, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are provided to guarantee consistency, purity, and reliability for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.