Description

9-Dihydroclarithromycin is a key intermediate in the synthesis of the widely used macrolide antibiotic, clarithromycin. This compound matters significantly for pharmaceutical manufacturers seeking to ensure the purity, efficacy, and regulatory compliance of their final antibiotic products. It is primarily needed by active pharmaceutical ingredient (API) producers and fine chemical suppliers serving the global pharmaceutical industry.

Application

• Pharmaceutical Intermediate: Critical precursor in the multi-step synthesis of the antibiotic clarithromycin.
• API Manufacturing: Used in the controlled production of clarithromycin Active Pharmaceutical Ingredient (API) under Good Manufacturing Practice (GMP) conditions.
• Research & Development: Serves as a reference standard and starting material in pharmaceutical R&D for novel macrolide derivatives and process optimization.
• Fine Chemical Synthesis: Employed in specialized organic synthesis for constructing complex molecular structures with antibacterial activity.

Basic Information

Product Name	9-Dihydroclarithromycin
CAS No.	131791-18-9
Molecular Formula	C38H69NO13
Molecular Weight	747.97 g/mol
Synonyms	9(S)-Dihydroclarithromycin; 6-O-Methyl-9(S)-dihydroerythromycin; Clarithromycin Impurity F; 9-Deoxo-9(S)-dihydroclarithromycin; 9(S)-Dihydro-6-O-methylerythromycin; N-Demethyl-9-dihydroclarithromycin (related); 9,10-Anhydro-9(S)-dihydroclarithromycin (related)
EINECS	Contact for details

Quality Control

Our 9-Dihydroclarithromycin is produced and tested to meet stringent quality standards suitable for pharmaceutical intermediate applications. Each batch undergoes comprehensive analysis including identification, purity assay, and impurity profiling via advanced chromatographic techniques. Certificates of Analysis (COA) detailing all test results are provided to ensure full traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.