Description

3,5-Cyclohexadiene-1,2-Diol,3,6-Difluoro-,cis-(9Ci) is a specialized fluorinated diol derivative of cyclohexadiene, serving as a valuable synthetic intermediate. Its unique cis-diol configuration and fluorine substitution make it a critical building block for introducing specific stereochemistry and fluorinated motifs into advanced molecular architectures. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where it is used to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a chiral scaffold for constructing sophisticated ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Advanced Material Research: Employed in the creation of fluorinated polymers and specialty coatings with unique surface properties and chemical resistance.
• Organic Synthesis Building Block: Utilized in complex multi-step syntheses to introduce the cis-1,2-diol functionality into complex natural products and fine chemicals.
• Fluorine Chemistry Research: A valuable reference compound and starting material for academic and industrial research exploring new fluorination methodologies and reaction pathways.

Basic Information

Product Name	3,5-Cyclohexadiene-1,2-Diol,3,6-Difluoro-,cis-(9Ci)
CAS No.	131788-75-5
Molecular Formula	C6H6F2O2
Molecular Weight	148.11 g/mol
Synonyms	cis-3,6-Difluorocyclohexa-3,5-diene-1,2-diol; 3,6-Difluorocyclohexa-3,5-diene-1,2-diol; 1,2-Dihydroxy-3,6-difluorocyclohexa-3,5-diene; (1R,2S)-3,6-Difluorocyclohexa-3,5-diene-1,2-diol; Fluorinated Catechol Derivative; 3,6-Difluoro-1,2-dihydroxybenzene (reduced form); cis-3,6-Difluoro-1,2-benzenediol (dihydro form)
EINECS	Contact for details

Quality Control

Our 3,5-Cyclohexadiene-1,2-Diol,3,6-Difluoro-,cis-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and isomeric integrity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your R&D and quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Isomeric Purity (cis-isomer)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.