Description

Sifaprazine CAS NO 131635-06-8 is a high-purity pharmaceutical intermediate and research chemical of significant interest in modern drug discovery. Its primary value lies in its role as a key building block for synthesizing novel therapeutic agents, particularly within the central nervous system (CNS) and psychiatric drug categories. This compound is essential for pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in developing new molecular entities and studying structure-activity relationships.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel psychotropic and neuroactive drug candidates.
• Research & Development: Used in medicinal chemistry for lead optimization, structure-activity relationship (SAR) studies, and pharmacological screening.
• Reference Standard: Serves as an analytical standard in quality control laboratories for method development and impurity profiling of active pharmaceutical ingredients (APIs).
• Fine Chemical Synthesis: Employed as a specialized building block for creating complex, high-value organic molecules with specific biological activity.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Product Name	Sifaprazine
CAS No.	131635-06-8
Molecular Formula	C18H19FN2O2
Molecular Weight	314.36 g/mol
Synonyms	1-[2-[4-(4-Fluorophenyl)-1-piperazinyl]ethyl]-1,3-dihydro-2H-benzimidazol-2-one; DU-27716; DU 27716; Sifaprazine Hydrochloride (salt form); 1-(2-(4-(4-Fluorophenyl)piperazin-1-yl)ethyl)-1,3-dihydro-2H-benzimidazol-2-one
EINECS	Contact for details

Quality Control

Our Sifaprazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR), purity assay by HPLC, and control of related substances and residual solvents. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider conditions under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.