Description

4-Nitrososulfamethoxazole is a specialized nitroso derivative of the sulfonamide antibiotic sulfamethoxazole. This compound serves as a crucial chemical intermediate and research standard in the development and analytical profiling of antimicrobial agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel sulfonamide-based therapeutics and the study of drug metabolism.

Application

• Pharmaceutical Intermediate: Key building block in the research and development of next-generation sulfonamide antibiotics and antimicrobial agents.
• Analytical Reference Standard: Used in high-performance liquid chromatography (HPLC) and mass spectrometry for method development, validation, and quality control of sulfamethoxazole and related compounds.
• Metabolite Studies: Employed in pharmacological and toxicological research to investigate the metabolic pathways and degradation products of sulfamethoxazole.
• Chemical Synthesis Research: Serves as a precursor or model compound in organic synthesis for introducing the nitroso functional group into complex molecules.
• Academic & Industrial Research: A valuable tool for universities and contract research organizations (CROs) studying sulfonamide chemistry, photochemistry, and oxidation processes.

Basic Information

Item	Detail
Product Name	4-Nitrososulfamethoxazole
CAS No.	131549-85-4
Molecular Formula	C10H11N4O4S
Molecular Weight	283.28 g/mol
Synonyms	4-Nitroso-sulfamethoxazole; N-(5-Methyl-3-isoxazolyl)-4-nitrosobenzenesulfonamide; Sulfamethoxazole Nitroso Derivative; 4-Nitroso-N-(5-methyl-3-isoxazolyl)benzenesulfonamide; SMX-NO; Nitroso Sulfamethoxazole
EINECS	Contact for details

Quality Control

Our 4-Nitrososulfamethoxazole is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) under an inert atmosphere to minimize oxidation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.