Description

Gadodiamide is a non-ionic, macrocyclic gadolinium-based contrast agent. This compound is critically important for its paramagnetic properties, which enhance magnetic resonance imaging (MRI) scans by improving the visibility of internal body structures. It is primarily needed by pharmaceutical manufacturers and diagnostic imaging centers for the formulation of safe and effective contrast media used in radiological procedures.

Application

• MRI Contrast Media: Primary active pharmaceutical ingredient (API) in injectable formulations for magnetic resonance imaging.
• Diagnostic Imaging Enhancement: Used to improve contrast in MRI scans of the central nervous system (CNS) and body.
• Pharmaceutical Intermediates: Serves as a key intermediate in the synthesis of advanced diagnostic agents.
• Research & Development: Utilized in biochemical and medical research for studying imaging techniques and contrast agent kinetics.
• Radiopharmaceuticals: Potential component in the development of novel diagnostic and therapeutic radiopharmaceuticals.

Basic Information

Product Name	Gadodiamide
CAS No.	131410-48-5
Molecular Formula	C16H28GdN5O8
Molecular Weight	573.66 g/mol
Synonyms	Gadodiamide; Gadodiamide hydrate; Gd-DTPA-BMA; Gadodiamidum; Gadodiamide (USP); Gadodiamide (Ph. Eur.); Omniscan (trade name); Gadolinium-diethylenetriaminepentaacetic acid bismethylamide
EINECS	Contact for details

Quality Control

Our Gadodiamide is manufactured under strict quality management systems to ensure it meets the stringent requirements for pharmaceutical active ingredients. Quality is assured through rigorous testing against relevant pharmacopoeial standards such as USP and Ph. Eur. Certificates of Analysis (COA) documenting purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (Gadodiamide anhydrous)	98.0% - 102.0%
pH (1% solution)	5.5 - 7.5
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets USP/ICH limits
Heavy Metals	≤ 20 ppm
Free Gadolinium	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Bacterial Endotoxins	< 0.25 EU/mg
Sterility (if applicable)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.