Description

Tri-tert-Butylphosphine Tetrafluoroborate is an organophosphorus salt widely recognized as a highly effective and air-stable precursor to the corresponding phosphine ligand. This compound is crucial in modern synthetic chemistry, offering a convenient and reliable source of the sterically demanding and electron-rich tri-tert-butylphosphine ligand. It is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for facilitating challenging cross-coupling and other catalytic transformations.

Application

• Catalytic Cross-Coupling Reactions: Serves as a vital precursor ligand for palladium-catalyzed Suzuki, Heck, Negishi, and Buchwald-Hartwig amination reactions.
• Pharmaceutical Intermediate Synthesis: Enables the efficient construction of complex carbon-carbon and carbon-heteroatom bonds in active pharmaceutical ingredient (API) development.
• Agrochemical Manufacturing: Used in the synthesis of novel herbicides, fungicides, and insecticides requiring robust catalytic systems.
• Materials Science Research: Facilitates the development of organic electronic materials, polymers, and novel ligands for metal-organic frameworks (MOFs).
• Homogeneous Catalysis Development: Acts as a key component in designing new catalyst systems for hydrogenation, hydroformylation, and other industrial processes.
• Academic & Industrial R&D: A staple reagent in research laboratories for methodological development and exploring new reaction pathways.

Basic Information

Product Name	Tri-tert-Butylphosphine Tetrafluoroborate
CAS No.	131274-22-1
Molecular Formula	C12H27P•BF4
Molecular Weight	292.13 g/mol
Synonyms	Tri-tert-butylphosphonium tetrafluoroborate; Tris(tert-butyl)phosphonium tetrafluoroborate; TTBP•HBF4; P(t-Bu)3•HBF4; Tris(1,1-dimethylethyl)phosphonium tetrafluoroborate; Phosphonium, tris(1,1-dimethylethyl)-, tetrafluoroborate(1-); Ligand Precursor
EINECS	Contact for details

Quality Control

Our Tri-tert-Butylphosphine Tetrafluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.