Description

Di-1-Adamantylphosphine is a highly sterically hindered tertiary phosphine ligand, prized for its exceptional electron-donating properties and air stability compared to many other phosphines. Its unique adamantyl-derived structure makes it a critical component in advanced catalytic systems, particularly for challenging cross-coupling and hydrogenation reactions. This specialty ligand is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require robust and selective catalysts.

Application

• Homogeneous Catalysis: As a key ligand in palladium- and nickel-catalyzed cross-coupling reactions (e.g., Suzuki-Miyaura, Buchwald-Hartwig amination).
• Pharmaceutical Intermediate Synthesis: Enabling the construction of complex carbon-heteroatom bonds in active pharmaceutical ingredient (API) development.
• Agrochemical Research: Used in the synthesis of novel herbicide and pesticide intermediates.
• Material Science: A precursor for the development of novel phosphine-based polymers and metal-organic frameworks (MOFs).
• Hydrogenation Catalysts: Serving as a ligand for ruthenium or rhodium complexes in selective reduction processes.
• Academic & Industrial R&D: A valuable tool for exploring new reaction methodologies in organometallic chemistry.

Basic Information

Product Name	Di-1-Adamantylphosphine
CAS No.	131211-27-3
Molecular Formula	C₂₀H₃₁P
Molecular Weight	302.43 g/mol
Synonyms	Bis(1-adamantyl)phosphine; Diadamantylphosphine; Di(1-adamantyl)phosphane; 1,1'-(Phosphinidene)bis(adamantane); Phosphinidynetris(adamantane) (related); PAd2 (common abbreviation)
EINECS	Contact for details

Quality Control

Our Di-1-Adamantylphosphine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, critical for reproducible catalytic performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity confirmation, and impurity profiles. Our quality system is designed to support cGMP and ISO-guided applications in research and development.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store under an inert atmosphere (argon or nitrogen) at 2-8°C. The product is easily oxidized and should be handled in a glove box or using standard Schlenk techniques to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.