Description

Trafermin is a recombinant human basic fibroblast growth factor (rhbFGF) that plays a critical role in cell proliferation, differentiation, and tissue repair. This high-purity protein is essential for advanced biomedical research and therapeutic development, offering a reliable tool for studying wound healing, angiogenesis, and neurotrophic effects. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and academic research institutions focused on regenerative medicine and novel drug discovery.

Application

• Biopharmaceutical R&D: Used as a key active ingredient or model compound in the development of wound healing agents and regenerative therapies.
• Cell Culture & Tissue Engineering: Serves as a potent growth factor supplement to promote the proliferation and maintenance of a wide variety of cell types, including fibroblasts, endothelial cells, and neural cells.
• Angiogenesis Research: Employed in studies investigating the formation of new blood vessels, crucial for cancer research and ischemic disease models.
• Neurobiology Studies: Applied in research on nerve regeneration, neuronal survival, and differentiation due to its neurotrophic properties.
• Wound Healing Models: Used in in vitro and in vivo models to study and accelerate the process of skin repair and regeneration.
• Diagnostic Development: Can be utilized as a standard or component in assay kits for quantifying bFGF levels in biological samples.

Basic Information

Product Name	Trafermin
CAS No.	131094-16-1
Molecular Formula	C690H1113N191O210S9
Molecular Weight	Approx. 16.4 kDa
Synonyms	Recombinant human basic Fibroblast Growth Factor; rhbFGF; rhFGF-2; rhFGF basic; Fiblast; bFGF; FGF-2; FGF-basic; Heparin-binding growth factor 2; HBGF-2; Trafermin (JAN/USAN)
EINECS	Contact for details

Quality Control

Our Trafermin is manufactured under strict quality management systems. Each batch is subjected to a comprehensive battery of analytical tests to ensure identity, purity, potency, and safety, meeting the stringent requirements for research and development use. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting specifications for purity, biological activity, endotoxin levels, and sterility.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized powder at -20°C or below. Reconstituted solutions should be aliquoted and stored at -20°C to -80°C to avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive).

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Identification (SDS-PAGE)	Complies
Purity (HPLC)	≥ 95.0%
Biological Activity (Cell Proliferation Assay)	≥ 1.0 x 106 IU/mg
Endotoxin	< 1.0 EU/μg
Protein Content (UV)	Complies
Sterility (Membrane Filtration)	Sterile
Solubility	Soluble in water or PBS

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.