Description

Aait Neurotoxin, Androctonus Australis is a highly purified, biologically active peptide toxin derived from the venom of the scorpion *Androctonus australis*. This compound is of significant value for advanced neurological research and pharmacological studies due to its specific and potent interaction with voltage-gated sodium channels. It is primarily required by research institutions, pharmaceutical R&D departments, and biotechnology companies focused on neurobiology, ion channel characterization, and novel therapeutic agent discovery.

Application

• Neuroscience Research: A key tool for studying the structure, function, and modulation of voltage-gated sodium channels (Nav channels) in neuronal cells.
• Pharmacological Profiling: Used in high-throughput screening assays to identify and evaluate potential new drugs targeting ion channelopathies, pain, and epilepsy.
• Toxin-Antitoxin Studies: Serves as a critical antigen in the development and validation of antivenoms and therapeutic neutralizing antibodies.
• Biochemical Reagent: Employed in protein-protein interaction studies and as a molecular probe to isolate specific channel subtypes.
• Academic & Industrial R&D: Fundamental research in universities and drug discovery pipelines in biopharma for validating novel targets.

Basic Information

Product Name	Aait Neurotoxin, Androctonus Australis
CAS No.	131092-86-9
Molecular Formula	C~200H~310N~60O~60S~6 (Approx., for full-length toxin)
Molecular Weight	~7-8 kDa (Approximate, varies with specific isoform and post-translational modifications)
Synonyms	AaIT; Androctonus australis insect toxin; Anti-insect scorpion toxin; β-toxin AaIT; Insect-selective neurotoxin AaIT; Neurotoxin AaH IT; CAS 131092-86-9; Androctonus australis Hector insect toxin.
EINECS	Contact for details

Quality Control

Our Aait Neurotoxin is produced and controlled under stringent conditions to ensure batch-to-batch consistency and high biological activity. Quality is verified through a comprehensive panel of analytical methods including HPLC for purity, mass spectrometry for identity confirmation, and functional bioassays for potency. A detailed Certificate of Analysis (COA) is provided with each batch, documenting purity, endotoxin levels, and biological activity specifications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Reconstituted solutions should be aliquoted and stored at -70°C to -80°C to prevent repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure containers are sealed under anhydrous conditions.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay (Bioactivity)	≥ 98% of stated activity
Endotoxin Level	< 1.0 EU/mg
Solubility	Soluble in aqueous buffers
Moisture Content (KF)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.