Description

Boc-L-Homocystine is a protected derivative of the sulfur-containing amino acid homocystine, featuring tert-butoxycarbonyl (Boc) groups on both amine functionalities. This compound is a critical building block in peptide synthesis, offering enhanced stability and solubility for complex solid-phase and solution-phase methodologies. It is essential for researchers and manufacturers in pharmaceutical development, biochemical research, and the production of specialized peptides and mimetics requiring controlled disulfide bridge formation.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Serves as a protected dimeric amino acid for the controlled introduction of homocystine residues, enabling the formation of disulfide bonds in synthetic peptides.
• Biochemical Research: Used in studies of sulfur metabolism, oxidative stress, and as a standard or reagent in analytical and metabolic pathway research.
• Proteomics & Bioconjugation: Employed in the development of cross-linking agents, affinity probes, and tools for protein structure-function studies.
• Material Science: Potential applications in creating novel biomimetic polymers and materials with specific redox-responsive properties.

Basic Information

Product Name	Boc-L-Homocystine
CAS No.	130981-51-0
Molecular Formula	C₂₂H₄₀N₄O₈S₂
Molecular Weight	552.69 g/mol
Synonyms	N,N'-Bis(tert-butoxycarbonyl)-L-homocystine; Di-Boc-L-homocystine; (2S,2'S)-2,2'-Bis[(tert-butoxycarbonyl)amino]-4,4'-dithiadi(butanoic acid); Boc-Hcy-OH (dimer); L-Homocystine, N,N'-bis(tert-butoxycarbonyl)-; tert-Butyl N-[(1S)-4-carboxy-1-[[(1S)-4-carboxy-1-[(2-methylpropan-2-yl)oxycarbonylamino]butyl]disulfanyl]butyl]carbamate
EINECS	Contact for details

Quality Control

Our Boc-L-Homocystine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Optical Rotation [α]²⁰D	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.