Description

Fmoc-Leu-Pro-Oh CAS NO 130832-25-6 is a protected dipeptide building block, specifically an Fmoc-protected leucine-proline derivative. This compound is a critical intermediate in solid-phase peptide synthesis (SPPS), enabling the controlled assembly of complex peptide sequences. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors who require high-purity, reliable reagents for peptide drug discovery and development.

Application

• Solid-Phase Peptide Synthesis (SPPS): A fundamental building block for the sequential assembly of custom peptide chains in research and production.
• Pharmaceutical Intermediates: Used in the synthesis of active pharmaceutical ingredients (APIs) for therapeutic peptides targeting various diseases.
• Bioconjugation and Probe Development: Serves as a component for creating labeled peptides used in diagnostic assays and biochemical research.
• Combinatorial Chemistry Libraries: Employed in the generation of diverse peptide libraries for high-throughput screening in drug discovery.
• Academic and Industrial R&D: A standard reagent in laboratories focused on peptide chemistry, structural biology, and medicinal chemistry.
• Custom Peptide Service Providers: A key raw material for companies offering bespoke peptide synthesis services.

Basic Information

Product Name	Fmoc-Leu-Pro-Oh
CAS No.	130832-25-6
Molecular Formula	C₂₆H₃₀N₂O₅
Molecular Weight	450.53 g/mol
Synonyms	Fmoc-Leu-Pro-OH; Fmoc-L-Leucyl-L-proline; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-leucyl-L-proline; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-methyl-N-((S)-pyrrolidine-2-carbonyl)pentanamide; Fmoc-Leu-Pro; Fmoc-L-Leu-L-Pro-OH; N-Fmoc-leucylproline; Fmoc-Leu-Pro dipeptide
EINECS	Contact for details

Quality Control

Our Fmoc-Leu-Pro-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification, to ensure it meets the high standards required for sensitive peptide synthesis applications. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Optical Rotation	-70° to -80° (c=1, DMF)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.