Description

1,3,4-Oxadiazole-2-Acetonitrile, 4-Acetyl-4,5-Dihydro-5,5-Dimethyl- is a high-value, functionalized heterocyclic building block with significant synthetic utility. This compound is essential for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily sought after by the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the oxadiazole ring's bioactivity.
• Material Science Research: Serves as a monomer or functional additive in the research of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a versatile scaffold or linker in the design of chemical probes, enzyme inhibitors, and bioconjugation reagents.
• Dye & Pigment Industry: Acts as an intermediate for synthesizing specialized heterocyclic dyes and optical brighteners.

Basic Information

Product Name	1,3,4-Oxadiazole-2-Acetonitrile, 4-Acetyl-4,5-Dihydro-5,5-Dimethyl-
CAS No.	130781-62-3
Molecular Formula	C8H11N3O2
Molecular Weight	181.19 g/mol
Synonyms	4-Acetyl-5,5-dimethyl-4,5-dihydro-1,3,4-oxadiazole-2-acetonitrile; 2-(4-Acetyl-5,5-dimethyl-4,5-dihydro-1,3,4-oxadiazol-2-yl)acetonitrile; 5,5-Dimethyl-4-acetyl-2-cyanomethyl-2-oxazoline; 130781-62-3; 4-Acetyl-5,5-dimethyl-2-(cyanomethyl)-2-oxazoline; 2-(4-Acetyl-5,5-dimethyl-4,5-dihydro-1,3,4-oxadiazol-2-yl)ethanenitrile
EINECS	Contact for details

Quality Control

Our 1,3,4-Oxadiazole-2-Acetonitrile, 4-Acetyl-4,5-Dihydro-5,5-Dimethyl- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for sensitive R&D and scale-up processes. Certificates of Analysis (COA) detailing all specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.