Description

Somatostatin, Azidonitrobenzoyl-Lys(9)-Iodo-Tyr(11)- is a chemically modified, photoactivatable analog of the endogenous peptide hormone somatostatin, identified by CAS No. 130772-41-7. This specialized derivative is engineered for advanced biochemical research, enabling precise cross-linking and target identification studies. It is an essential tool for researchers in pharmaceutical development and molecular biology investigating somatostatin receptor (SSTR) signaling pathways, drug discovery, and proteomic mapping.

Application

• Photoaffinity Labeling: A critical reagent for covalently tagging and identifying somatostatin receptor subtypes and their interacting protein partners in complex biological systems.
• Biochemical Research: Used in structure-activity relationship (SAR) studies to elucidate the binding site and conformational requirements of somatostatin analogs.
• Drug Discovery Platforms: Serves as a key molecular probe in high-throughput screening assays to discover and optimize new SSTR-targeted therapeutics.
• Proteomics and Target Identification: Facilitates the isolation and characterization of receptor complexes for mapping signaling networks and off-target effects.
• Radioligand Development: Acts as a precursor or template for developing iodinated or tritiated radiotracers used in receptor autoradiography and binding assays.

Basic Information

Product Name	Somatostatin, Azidonitrobenzoyl-Lys(9)-Iodo-Tyr(11)-
CAS No.	130772-41-7
Molecular Formula	C76H105N19O19S2
Molecular Weight	1636.9 g/mol
Synonyms	ANB-Lys(9)-Iodo-Tyr(11)-Somatostatin-14; p-Azidonitrobenzoyl-Lys(9)-Iodo-Tyr(11)-Somatostatin; Photoactivatable Somatostatin Analog; SSTR Photoaffinity Probe; SRIF-14 (ANB-Lys9, I-Tyr11); Somatotropin Release-Inhibiting Factor Analog; 130772-41-7; Azidonitrobenzoyl-modified SRIF
EINECS	Contact for details

Quality Control

Our Somatostatin, Azidonitrobenzoyl-Lys(9)-Iodo-Tyr(11)- is manufactured under controlled conditions to ensure batch-to-batch consistency and high chemical purity suitable for sensitive research applications. Each lot undergoes rigorous analytical testing, including HPLC for purity and mass spectrometry for identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This compound is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%
Solubility	Soluble in DMSO, Acetonitrile/Water mixtures

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.