Description

Scorpion Toxin Aah It4 is a highly purified, biologically active peptide toxin isolated from the venom of the scorpion *Androctonus australis hector*. This compound is a critical research tool for studying voltage-gated sodium (Nav) channels, offering high specificity and potency. It is essential for neuroscientists, pharmacologists, and toxicologists engaged in ion channel research, drug discovery for neurological disorders, and the development of novel bio-insecticides.

Application

• Neuroscience Research: A key tool for probing the structure, function, and pharmacology of specific subtypes of voltage-gated sodium channels (Nav channels).
• Drug Discovery & Development: Used in high-throughput screening and validation assays to identify and characterize new therapeutic candidates targeting ion channels for pain, epilepsy, and cardiac conditions.
• Toxicology Studies: Serves as a reference standard in venom research and for understanding the mechanism of action of scorpion toxins.
• Academic & Institutional Research: Fundamental reagent for university and government labs studying cellular excitability, neurotoxin action, and signal transduction.
• Biopharmaceutical Production: Can be used in the development and quality control of antivenoms and other biotherapeutics derived from venom components.

Basic Information

Product Name	Scorpion Toxin Aah It4
CAS No.	130726-76-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	AaH IT4; Toxin AahIt4; Androctonus australis Hector Insect Toxin 4; Nav Channel Toxin Aah It4; Scorpion Venom Peptide IT4; Anti-Insect Toxin 4
EINECS	Contact for details

Quality Control

Our Scorpion Toxin Aah It4 is produced and handled under stringent conditions to ensure batch-to-batch consistency and biological activity. Each lot is characterized using advanced analytical techniques, including mass spectrometry and HPLC, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, bioactivity, and endotoxin levels is provided with every shipment to support your research integrity and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake. Aliquot reconstituted solutions to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Biological Activity	Confirmed by functional assay
Endotoxin Level	< 1.0 EU/µg
Solubility	Soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.