Description

3-Iodophenylacetonitrile is a versatile halogenated aromatic nitrile building block of significant importance in advanced organic synthesis. Its core value lies in providing a reactive iodine substituent and a cyano group, enabling diverse functionalization and carbon-carbon bond formation. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, serving as a key intermediate for the development of active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated aromatic structure.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and advanced polymers with specific electronic properties.
• Chemical Biology Probes: Utilized to create labeled compounds and molecular probes for studying biological pathways and mechanisms.
• Custom Synthesis and R&D: A valuable starting material for contract research organizations (CROs) and fine chemical companies engaged in custom synthesis projects.

Basic Information

Product Name	3-Iodophenylacetonitrile
CAS No.	130723-54-5
Molecular Formula	C8H6IN
Molecular Weight	243.05 g/mol
Synonyms	(3-Iodophenyl)acetonitrile; 3-Iodobenzyl cyanide; m-Iodophenylacetonitrile; 2-(3-Iodophenyl)acetonitrile; α-Cyano-3-iodotoluene; 3-Iodobenzeneacetonitrile; 3-Iodobenzylnitrile; (m-Iodophenyl)acetonitrile
EINECS	Contact for details

Quality Control

Our 3-Iodophenylacetonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, GC, and NMR, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.