Description

3-Benzyloxy-5-Bromobenzotrifluoride is a high-value, multi-functional aromatic intermediate featuring both a benzyloxy protecting group and a bromine substituent on a trifluoromethylbenzene core. This unique molecular architecture makes it a critical building block for the synthesis of complex organic molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and life science industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring the trifluoromethyl group for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the bromine atom serves as a handle for further functionalization via cross-coupling reactions.
• Liquid Crystal & OLED Materials: Serves as a building block for creating specialized aromatic cores used in electronic display technologies and organic light-emitting diodes.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Chemical Research & Development: A versatile reagent for academic and industrial research in medicinal chemistry and material science for exploring new chemical entities.
• Functional Polymer Monomer: Can be incorporated into polymer backbones to impart specific properties like solubility, thermal stability, or unique optical characteristics.

Basic Information

Item	Detail
Product Name	3-Benzyloxy-5-Bromobenzotrifluoride
CAS No.	130723-14-7
Molecular Formula	C14H10BrF3O
Molecular Weight	331.13 g/mol
Synonyms	5-Bromo-3-(benzyloxy)benzotrifluoride; 1-Benzyloxy-3-bromo-5-(trifluoromethyl)benzene; 3-Bromo-5-(benzyloxy)benzotrifluoride; 3-Benzyloxy-5-bromo-α,α,α-trifluorotoluene; 5-Bromo-3-(phenylmethoxy)benzotrifluoride; (3-Benzyloxy-5-bromophenyl)trifluoromethane; Benzene, 1-bromo-3-(phenylmethoxy)-5-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Every batch of 3-Benzyloxy-5-Bromobenzotrifluoride is produced and tested under a strict quality management system. We ensure the product meets the high-purity standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids, strong bases, and strong oxidizing agents. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.