Description

Butyloxycarbonyl-Aminoisobutyryl-Alanyl-Leucyl-Alanyl-Leucyl-Aminoisobutyryl-Leucyl-Alanyl-Leucyl-Aminoisobutyryl Methyl Ester is a high-purity, custom synthetic peptide derivative designed for advanced research and development applications. This compound serves as a critical building block or intermediate in the synthesis of complex peptides and peptidomimetics, offering precise structural control. It is primarily utilized by pharmaceutical R&D laboratories and biotechnology companies engaged in drug discovery, particularly for developing novel therapeutic agents.

Application

• Pharmaceutical Research & Development: As a key intermediate in the solid-phase or solution-phase synthesis of novel peptide-based drug candidates.
• Peptidomimetic Design: Used to incorporate non-natural amino acid residues (Aminoisobutyryl) to enhance metabolic stability and bioavailability of peptide leads.
• Bioconjugation & Probe Development: Serves as a scaffold for attaching labels, tags, or other functional groups in the creation of diagnostic or imaging probes.
• Structure-Activity Relationship (SAR) Studies: Essential for constructing specific peptide sequences to investigate biological activity and optimize therapeutic properties.
• Academic & Institutional Research: Employed in biochemical and biophysical studies to understand protein-protein interactions and peptide folding.
• Pre-clinical Development: Supports the production of materials for toxicology, pharmacokinetics, and formulation studies.

Basic Information

Product Name	Butyloxycarbonyl-Aminoisobutyryl-Alanyl-Leucyl-Alanyl-Leucyl-Aminoisobutyryl-Leucyl-Alanyl-Leucyl-Aminoisobutyryl Methyl Ester
CAS No.	130640-26-5
Molecular Formula	C58H100N12O16
Molecular Weight	1221.5 g/mol (approx.)
Synonyms	Boc-Aib-Ala-Leu-Ala-Leu-Aib-Leu-Ala-Leu-Aib-OMe; Boc-(Aib)2-(Ala)2-(Leu)4-OMe; t-Butyloxycarbonyl-Aminoisobutyryl-Alanyl-Leucyl-Alanyl-Leucyl-Aminoisobutyryl-Leucyl-Alanyl-Leucyl-Aminoisobutyryl Methyl Ester; BOC-AIB-ALA-LEU-ALA-LEU-AIB-LEU-ALA-LEU-AIB-OCH3; Peptide Derivative CAS 130640-26-5; Custom Synthetic Peptide Intermediate; N-α-Boc-decapeptide methyl ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, chiral integrity, and solvent residues are available upon request. We adhere to cGMP principles for manufacturing critical intermediates to support our clients' regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 90.0% (by weight)
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Chiral Purity	≥ 99.0% ee

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.