Description

3-Amino-n-[(1,1-Dimethylethoxy)Carbonyl]-D- Alanine Methyl Ester is a protected D-amino acid derivative, serving as a crucial chiral building block in advanced organic synthesis. Its value lies in providing a stereochemically defined scaffold for constructing complex peptide-based molecules and active pharmaceutical ingredients (APIs). This high-purity intermediate is essential for research and production in the pharmaceutical industry, particularly for developing novel therapeutics, peptide hormones, and diagnostic agents where precise chirality is critical for biological activity.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel peptide-based drugs and APIs.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to introduce D-alanine derivatives into peptide chains.
• Protease Inhibitor Development: A building block for creating inhibitors targeting specific proteolytic enzymes.
• Chemical Biology Research: Employed in the study of peptide structure-activity relationships and receptor-ligand interactions.
• Diagnostic Agent Precursor: Intermediate in the production of radiolabeled or tagged peptides for imaging and diagnostics.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or starting material in stereoselective chemical transformations.

Basic Information

Product Name	3-Amino-n-[(1,1-Dimethylethoxy)Carbonyl]-D- Alanine Methyl Ester
CAS No.	130622-06-9
Molecular Formula	C10H20N2O4
Molecular Weight	232.28 g/mol
Synonyms	Boc-D-2,3-diaminopropionic acid methyl ester; (R)-Methyl 3-((tert-butoxycarbonyl)amino)-2-aminopropanoate; Methyl (R)-3-((tert-butoxycarbonyl)amino)-2-aminopropanoate; Boc-D-Dap-OMe; Boc-D-2,3-diaminopropanoic acid methyl ester; (R)-2-Amino-3-[(tert-butoxycarbonyl)amino]propanoic acid methyl ester; tert-Butyl ((R)-1-methoxy-1-oxo-3-aminopropan-2-yl)carbamate
EINECS	Contact for details

Quality Control

Our 3-Amino-n-[(1,1-Dimethylethoxy)Carbonyl]-D- Alanine Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.