Description

L-Proline, 1-(Fluoroacetyl)- (9Ci) is a specialized fluorinated derivative of the amino acid L-proline, designed for advanced synthetic applications. This compound is valued for its role as a key building block in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought by researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel bioactive compounds and peptidomimetics.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly protease inhibitors and other targeted therapeutics.
• Peptidomimetic Research: Used to incorporate fluorinated motifs into peptide backbones, enhancing metabolic stability and binding affinity in drug design.
• Agrochemical Synthesis: Serves as a building block for developing advanced, fluorinated active ingredients with improved efficacy and environmental profiles.
• Bioconjugation & Probe Development: Utilized in creating fluorescent or radioactive probes for biochemical and diagnostic applications.
• Academic & R&D Laboratories: Employed in methodological studies and the exploration of new fluorination chemistry and asymmetric synthesis routes.
• Fine Chemical Production: Acts as a chiral synthon for the manufacture of high-value, optically active compounds.

Basic Information

Item	Details
Product Name	L-Proline, 1-(Fluoroacetyl)- (9Ci)
CAS No.	130603-12-2
Molecular Formula	C7H10FNO3
Molecular Weight	175.16 g/mol
Synonyms	1-(Fluoroacetyl)-L-proline; N-Fluoroacetyl-L-proline; (S)-1-(2-Fluoroacetyl)pyrrolidine-2-carboxylic acid; L-Proline, N-(fluoroacetyl)-; Fluoroacetic acid L-prolinamide; N-Fluoroacety-L-proline; N-(Fluoroacetyl)proline; (2S)-1-(2-Fluoroacetyl)pyrrolidine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of L-Proline, 1-(Fluoroacetyl)- (9Ci) is produced and tested under strict quality management protocols to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as assay, chiral purity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is sensitive to light and may be incompatible with strong bases and fluorides. Keep away from heat and ignition sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.