Description

Mastoparan 17 CAS NO 130571-28-7 is a synthetic, amphiphilic peptide toxin derived from wasp venom, known for its potent biological activity as a G-protein activator. This compound is a critical research tool for studying cellular signaling pathways, particularly those involving phospholipase C and calcium mobilization. It is essential for researchers and developers in the fields of pharmacology, biochemistry, and cell biology who require high-purity, well-characterized bioactive peptides for mechanistic studies and drug discovery.

Application

• Biochemical Research: A fundamental tool for investigating G-protein coupled receptor (GPCR) signaling, mast cell degranulation, and phospholipase C (PLC) activation mechanisms.
• Pharmacology & Drug Discovery: Used as a reference standard and a probe to screen for inhibitors or modulators of G-protein activity and calcium signaling pathways.
• Cell Biology Studies: Employed to study exocytosis, membrane fusion events, and ion channel modulation in various cell types.
• Neuroscience Research: Applied in studies of neurotransmitter release and the role of G-proteins in neuronal signal transduction.
• Immunology Research: Utilized to investigate mast cell and basophil activation, histamine release, and inflammatory responses.
• Peptide Chemistry & Conjugation: Serves as a model amphiphilic peptide for structure-activity relationship (SAR) studies and for developing peptide-based conjugates.

Basic Information

Product Name	Mastoparan 17
CAS No.	130571-28-7
Molecular Formula	C78H133N25O19
Molecular Weight	1700.06 g/mol
Synonyms	Mastoparan 17; Mastoparan XVII; Ile-Asn-Leu-Lys-Ala-Leu-Ala-Ala-Leu-Ala-Lys-Lys-Ile-Leu-NH2; INLKALAALAKKIL-NH2; H-INLKALAALAKKIL-NH2; G-protein activator peptide; Wasp venom peptide 17
EINECS	Contact for details

Quality Control

Our Mastoparan 17 is produced under stringent conditions to ensure batch-to-batch consistency and high biological activity. Each lot undergoes comprehensive analytical testing, including HPLC for purity verification and Mass Spectrometry (MS) for identity confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting purity, peptide content, and other critical parameters to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Amino Acid Analysis	Conforms to theoretical composition
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.