Description

3-Chloro-4-Fluorothiobenzamide is a high-purity fluorinated thiobenzamide derivative, serving as a critical advanced pharmaceutical intermediate. Its value lies in its unique molecular scaffold, which is essential for synthesizing novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new drug candidates and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry research for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and pesticides, leveraging the fluorine and chlorine substituents for enhanced bioactivity.
• Ligand and Catalyst Precursor: Serves as a precursor for specialized ligands in transition metal catalysis and organocatalysis for asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials and liquid crystals due to its conjugated aromatic system and halogen atoms.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific fluorinated aromatic intermediates.

Basic Information

Product Name	3-Chloro-4-Fluorothiobenzamide
CAS No.	130560-97-3
Molecular Formula	C7H5ClFNS
Molecular Weight	189.64 g/mol
Synonyms	3-Chloro-4-fluorobenzenecarbothioamide; 4-Fluoro-3-chlorothiobenzamide; Benzenecarbothioamide, 3-chloro-4-fluoro-; 3-Chloro-4-fluorobenzothioamide; Thiobenzamide, 3-chloro-4-fluoro-; 130560-97-3; 3-Chloro-4-fluoro-benzenecarbothioamide
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Fluorothiobenzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.