Description

2-O,3-O:4-O,6-o-Bis(Isopropylidene)-β-D-Mannopyranosyl Cyanide is a protected glycosyl donor, a key synthetic intermediate in carbohydrate and nucleoside chemistry. Its primary value lies in enabling the stereoselective construction of complex glycosidic bonds, which is critical for developing active pharmaceutical ingredients (APIs) and other bioactive molecules. This high-purity building block is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality intermediates for advanced synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of nucleoside analogs and other glycosylated drug candidates.
• Antiviral & Anticancer Drug Development: Used in the research and production of novel therapeutic agents targeting viral infections and cancer.
• Carbohydrate Chemistry Research: Serves as a key starting material for the synthesis of complex oligosaccharides and glycoconjugates.
• Glycosylation Reactions: Acts as a mannosyl donor in stereocontrolled glycosylation protocols to create specific anomeric linkages.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of specialty chemicals and advanced materials requiring precise sugar motifs.
• Process Development & Scale-up: Suitable for use in process chemistry from laboratory-scale research to pilot plant and commercial production.

Basic Information

Product Name	2-O,3-O:4-O,6-o-Bis(Isopropylidene)-β-D-Mannopyranosyl Cyanide
CAS No.	130495-50-0
Molecular Formula	C₁₃H₁₉NO₆
Molecular Weight	285.29 g/mol
Synonyms	2,3:4,6-Di-O-isopropylidene-β-D-mannopyranosyl cyanide; 2,3:4,6-Di-O-isopropylidene-α-D-mannopyranosyl cyanide (common name); Diacetone mannose cyanide; Di-O-isopropylidene mannopyranosyl cyanide; 1-Cyano-2,3:4,6-di-O-isopropylidene-β-D-mannopyranose; Protected mannosyl cyanide; Mannose diacetonide cyanohydrin
EINECS	Contact for details

Quality Control

Our 2-O,3-O:4-O,6-o-Bis(Isopropylidene)-β-D-Mannopyranosyl Cyanide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.