Description

2-O,3-O:5-O,6-o-Bis(Isopropylidene)-α-D-Mannofuranosyl Cyanide is a protected carbohydrate derivative, specifically a key chiral intermediate in organic synthesis. This compound matters for its role in constructing complex sugar-based molecules, offering a versatile and reactive cyanide handle for nucleophilic addition and chain extension reactions. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of nucleoside analogs, antiviral agents, and other bioactive glycoconjugates.

Application

• Pharmaceutical Intermediate: A crucial chiral building block for the synthesis of nucleoside analogs and antiviral drugs.
• Glycochemistry Research: Used in the preparation of complex oligosaccharides and glycoconjugates for biological studies.
• Carbohydrate Chemistry: Serves as a protected mannose derivative for stereoselective glycosylation and functional group transformations.
• Chemical Biology Probes: Acts as a precursor for labeled sugar molecules used in metabolic pathway tracing and imaging.
• Process Development: Employed in scale-up and optimization of synthetic routes for high-value fine chemicals.

Basic Information

Product Name	2-O,3-O:5-O,6-o-Bis(Isopropylidene)-α-D-Mannofuranosyl Cyanide
CAS No.	130468-52-9
Molecular Formula	C13H19NO5
Molecular Weight	269.29 g/mol
Synonyms	1,2:5,6-Di-O-isopropylidene-α-D-mannofuranosyl cyanide; 1,2:5,6-Di-O-isopropylidene-α-D-mannofuranose cyanohydrin; 3,4-Dihydro-2H-pyran-3-carbonitrile, 5,6-bis(1-methylethylidene)tetrahydro-2,2-dimethyl-, (3R,5S,6R)-; Diacetone mannose cyanohydrin; D-Mannose, 1,2:5,6-di-O-(1-methylethylidene)-, cyanohydrin, α-D-; Isopropylidene mannofuranosyl cyanide
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material with typical purity levels suitable for research and process development. Certificates of Analysis (COA) detailing identity, purity (by HPLC/NMR), and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.