Description

2-Oxoglutarate-Malate Carrier Protein is a specialized mitochondrial transport protein critical for cellular metabolism. This compound is essential for facilitating the exchange of key metabolic intermediates across the inner mitochondrial membrane, playing a vital role in energy production and biosynthetic pathways. It is primarily utilized by researchers and developers in the fields of biochemistry, molecular biology, and pharmaceutical development for studying mitochondrial function and metabolic diseases.

Application

• Biochemical Research: Used as a key reagent in studies of mitochondrial transport mechanisms and the citric acid (Krebs) cycle.
• Enzyme Activity Assays: Serves as a substrate or carrier component in assays for dehydrogenase and transaminase enzymes.
• Metabolic Pathway Analysis: Essential for in vitro reconstruction of metabolic pathways to investigate energy metabolism and anapleurosis.
• Pharmaceutical Development: Employed in target validation and screening for drugs aimed at metabolic disorders, cancer, and neurodegenerative diseases.
• Diagnostic Kit Manufacturing: Incorporated into kits for clinical diagnostics related to mitochondrial dysfunction.
• Cell Culture & Metabolism Studies: Used to supplement media in studies requiring precise control of mitochondrial substrate levels.

Basic Information

Product Name	2-Oxoglutarate-Malate Carrier Protein
CAS No.	130433-50-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	OGCP; 2-Oxoglutarate/Malate Carrier; Oxoglutarate-Malate Carrier Protein; Mitochondrial 2-Oxoglutarate Carrier; SLC25A11 Protein; 2-Oxoglutarate Translocator; Malate-2-Oxoglutarate Antiporter; DIC (2-Oxoglutarate Carrier)
EINECS	Contact for details

Quality Control

Our 2-Oxoglutarate-Malate Carrier Protein is produced and handled under stringent quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and functional activity. Certificates of Analysis (COA) detailing specifications such as protein concentration, purity by SDS-PAGE, and functional activity are available upon request to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, consider aliquoting to avoid repeated freeze-thaw cycles and store under inert conditions if necessary.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (IR)	Conforms to structure
Purity (SDS-PAGE)	≥ 90%
Protein Content (BCA)	≥ 85%
Biological Activity	Contact for details
Endotoxin Level (LAL)	< 1.0 EU/mg
Solubility	Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.