Description

Landomycin A is a potent macrolide antibiotic belonging to the landomycin family, known for its significant antitumor and antibacterial properties. This compound is a critical intermediate and reference standard in pharmaceutical research and development, particularly for studying novel anticancer agents and antibiotic mechanisms. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and academic sectors who require high-purity bioactive compounds for drug discovery and biochemical studies.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel antitumor and antibacterial drugs.
• Anticancer Agent Studies: Used in biochemical and cellular assays to investigate mechanisms of action against various cancer cell lines.
• Microbiological Research: Employed as a tool compound to study antibiotic activity, resistance mechanisms, and structure-activity relationships (SAR) within the macrolide class.
• Biochemical Standard: Utilized as a high-purity calibrant in analytical methods such as HPLC and LC-MS for quality control and metabolic studies.
• Academic & Institutional Research: Provides a foundational compound for university and institutional labs conducting research in medicinal chemistry and pharmacology.

Basic Information

Item	Detail
Product Name	Landomycin A
CAS No.	130432-93-8
Molecular Formula	C39H48N2O13
Molecular Weight	752.81 g/mol
Synonyms	Landomycin A1; Landomycin A; Antibiotic Landomycin A; Urdamycin A; Landomycin A (Urdamycin A); 5,12-Dideoxy-12-oxo-4-O-(2,6-dideoxy-4-O-[(2S,4S,5S)-4,5-dihydroxy-6-methyl-3-(methylamino)oxan-2-yl]-α-L-lyxo-hexopyranosyl)-3-C-methyl-8,11-O-[1-(dimethylamino)ethylidene]-6-O-methylerythronolide A 11,12-carbonate; (2R,3S,4S,5R,8R,9S,10S,11R,12S,13S)-5-[(2S,3S,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-9-ethyl-2,3,4,10,11,12-hexahydroxy-8,13-dimethoxy-6-methyl-3,4-epoxy-1-oxacyclotridecane-7,13-dione
EINECS	Contact for details

Quality Control

Our Landomycin A is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines to support our clients' regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and potency.

Specification

Item	Specification
Appearance	Yellow to brownish-yellow powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.