Description

(R )-(2-Amino-1-Phenyl-Ethyl)-Carbamic Acid Benzyl Ester is a high-purity chiral intermediate of significant importance in asymmetric synthesis. This compound matters because it provides a key building block for the construction of complex molecules with defined stereochemistry, which is critical for developing active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the development of new therapeutic agents and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular research.
• Asymmetric Catalyst Ligand Precursor: Used in the development and preparation of chiral ligands for metal-catalyzed asymmetric reactions.
• Peptidomimetic Research: Serves as a protected β-amino acid derivative in the design and synthesis of novel peptide analogs and enzyme inhibitors.
• Agrochemical Synthesis: Employed in the production of chiral active ingredients for herbicides, fungicides, and insecticides.
• Academic & Process Chemistry: A valuable reagent for methodological development in organic synthesis and scale-up process optimization in university and industrial R&D labs.

Basic Information

Product Name	(R )-(2-Amino-1-Phenyl-Ethyl)-Carbamic Acid Benzyl Ester
CAS No.	130406-35-8
Molecular Formula	C16H18N2O2
Molecular Weight	270.33 g/mol
Synonyms	(R)-N-Cbz-1-Phenylethylenediamine; (R)-1-Phenylethane-1,2-diamine, N2-Cbz-protected; (R)-2-[(Benzyloxy)carbonyl]amino]-1-phenylethylamine; (R)-N2-[(Benzyloxy)carbonyl]-1,2-diphenylethylenediamine; (R)-Cbz-PEDA; (R)-1-Amino-2-(N-Cbz-amino)-1-phenylethane; Benzyl (R)-(2-amino-1-phenylethyl)carbamate; (R)-N-Cbz-1,2-Diamino-1-phenylethane
EINECS	Contact for details

Quality Control

Our (R )-(2-Amino-1-Phenyl-Ethyl)-Carbamic Acid Benzyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.