Description

C-Reactive Protein Fragment 77-82 is a defined synthetic peptide sequence derived from the acute-phase reactant, C-reactive protein (CRP). This fragment is a critical research tool for investigating the structure-function relationships and biological activities of CRP, particularly its role in inflammation and innate immunity. It is primarily utilized by researchers and developers in the fields of immunology, biochemistry, and pharmaceutical discovery for assay development, antibody production, and mechanistic studies.

Application

• Biochemical Research: Used as a reference standard or antigen in studies exploring the inflammatory pathways and ligand-binding properties of C-reactive protein.
• Immunoassay Development: Serves as a key component in the development and calibration of ELISA and other immunoassays designed to detect or quantify CRP or its fragments.
• Antibody Production & Characterization: Acts as an immunogen for generating monoclonal or polyclonal antibodies specific to this region of the CRP molecule.
• Pharmaceutical Screening: Employed in high-throughput screening (HTS) platforms to identify potential drug candidates that modulate CRP-mediated inflammatory responses.
• Peptide Mapping & Proteomics: Used as a standard in mass spectrometry and chromatographic analyses for protein characterization and peptide sequencing.
• Academic & Institutional Research: Fundamental tool for university and research institute labs focused on cardiovascular disease, chronic inflammation, and related pathologies.

Basic Information

Product Name	C-Reactive Protein Fragment 77-82
CAS No.	130349-01-8
Molecular Formula	C30H50N10O11
Molecular Weight	702.78 g/mol
Synonyms	CRP (77-82); Human C-Reactive Protein Fragment (77-82); CRP Peptide (77-82); H-Cys-Glu-Leu-Ala-Glu-Phe-OH; CEL-AEF; C-Reactive Protein (77-82) human; Synthetic CRP fragment
EINECS	Contact for details

Quality Control

Our C-Reactive Protein Fragment 77-82 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and MS for identity confirmation, to ensure it meets the high standards required for research applications. A Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Amino Acid Analysis	Within ±10% of theoretical
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water or buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.