Description

5Carboxy Meloxicam is a key carboxylic acid derivative and a primary metabolite of the non-steroidal anti-inflammatory drug (NSAID) Meloxicam. This compound is of significant importance in pharmaceutical research and development, serving as a critical reference standard and a vital synthetic intermediate. It is primarily needed by pharmaceutical manufacturers, analytical laboratories, and research institutions engaged in drug metabolism studies, impurity profiling, and the development of novel therapeutic agents.

Application

• Pharmaceutical Reference Standard: Used as a certified standard for the identification and quantification of the 5'-carboxy metabolite in bioanalytical studies and pharmacokinetic research.
• Metabolite Synthesis & Research: Acts as a crucial intermediate in the synthesis of other Meloxicam metabolites for comprehensive drug metabolism and safety (ADME/Tox) profiling.
• Impurity Standard: Employed as a specified impurity standard in the quality control (QC) and stability testing of Meloxicam active pharmaceutical ingredient (API) and finished dosage forms to ensure product purity and safety.
• Analytical Method Development: Serves as a key analyte for developing and validating high-performance liquid chromatography (HPLC) and LC-MS/MS methods in regulatory and research settings.
• Biochemical Research: Utilized in studies investigating the structure-activity relationships (SAR) and the metabolic pathways of oxicam-class NSAIDs.

Basic Information

Product Name	5Carboxy Meloxicam
CAS No.	130262-93-0
Molecular Formula	C15H13N3O5S2
Molecular Weight	379.41 g/mol
Synonyms	5'-Carboxymeloxicam; 5-Carboxy Meloxicam; Meloxicam Carboxylic Acid; 4-Hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide-5-carboxylic acid; UNII-0V4P7JEC5P; 5-COOH Meloxicam; Meloxicam metabolite; 1,2-Benzothiazine-3-carboxamide, 4-hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-, 1,1-dioxide, 5-carboxy-
EINECS	Contact for details

Quality Control

Our 5Carboxy Meloxicam is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and MS, to ensure it meets high-purity standards suitable for research and analytical applications. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	Off-white to pale yellow powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.