Description

5Hydroxy Meloxicam is a key pharmaceutical intermediate and metabolite of the non-steroidal anti-inflammatory drug (NSAID) Meloxicam. This compound is critical for research and development in pharmacology, particularly in studies related to drug metabolism, pharmacokinetics, and the synthesis of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, analytical reference standard producers, and manufacturers engaged in the development of advanced NSAID formulations.

Application

• Pharmaceutical Reference Standard: Used as a high-purity certified reference material (CRM) for analytical method development and validation in quality control laboratories.
• Metabolite Studies: Essential for in-vitro and in-vivo research investigating the metabolic pathways, bioavailability, and excretion profiles of Meloxicam.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a crucial building block or intermediate in the synthetic pathways for developing new Meloxicam analogs or prodrugs.
• Biomedical Research: Employed in biochemical assays and studies aimed at understanding the mechanism of action and side-effect profiles related to COX-2 inhibition.
• Impurity Profiling: Used to identify, quantify, and qualify process-related impurities or degradation products in Meloxicam bulk drug and finished dosage forms.

Basic Information

Product Name	5Hydroxy Meloxicam
CAS No.	130262-92-9
Molecular Formula	C14H13N3O5S2
Molecular Weight	367.40 g/mol
Synonyms	5-Hydroxymeloxicam; 4-Hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide; Meloxicam Metabolite; 5-OH Meloxicam; UNII-8BCT82K1YE; 1,2-Benzothiazine-3-carboxamide, 4-hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-, 1,1-dioxide
EINECS	Contact for details

Quality Control

Our 5Hydroxy Meloxicam is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and MS, to ensure it meets stringent specifications for research and pharmaceutical use. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting compliance with cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.