Description

2,2-Difluoro-2-Phenyl-Ethanol is a fluorinated aromatic alcohol building block of significant interest in advanced organic synthesis. Its value lies in the unique reactivity imparted by the difluoromethylenol moiety, which is crucial for modulating the physicochemical properties of target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, as well as by manufacturers of specialty materials and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of fluorinated drug candidates, where fluorine atoms are introduced to enhance metabolic stability, bioavailability, and binding affinity.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides that benefit from the lipophilicity and stability conferred by fluorine.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated aromatic compounds for electronic display and lighting applications, improving charge transport and thermal stability.
• Polymer Modification: Employed to introduce fluorinated phenyl groups into polymer backbones or side chains, altering surface properties, chemical resistance, and optical characteristics.
• Organic Synthesis Building Block: Utilized in various name reactions (e.g., Mitsunobu, esterification) to create complex fluorinated molecules for research and scale-up projects.
• Flavor & Fragrance Industry: Potential use in creating novel, stable aromatic compounds with unique organoleptic profiles.

Basic Information

Product Name	2,2-Difluoro-2-Phenyl-Ethanol
CAS No.	129973-51-9
Molecular Formula	C8H8F2O
Molecular Weight	158.15 g/mol
Synonyms	α,α-Difluoro-β-hydroxyethylbenzene; 2,2-Difluoro-1-phenylethanol; 1-Phenyl-2,2-difluoroethanol; (2,2-Difluoro-2-phenylethyl) alcohol; Benzeneethanol, 2,2-difluoro-; 2-Phenyl-2,2-difluoroethanol; DFPE
EINECS	Contact for details

Quality Control

Our 2,2-Difluoro-2-Phenyl-Ethanol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of our global B2B clients in regulated industries. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.