Description

Boc-2,4-Dimethylaniline is a high-purity, protected aniline derivative, essential as a key building block in advanced organic synthesis. Its primary value lies in providing a reactive amine group that is temporarily shielded by the acid-labile tert-butoxycarbonyl (Boc) protecting group, enabling precise, sequential reactions. This compound is critically needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing substituted aniline moieties.
• Peptide & Protein Chemistry: Used in solid-phase peptide synthesis (SPPS) and other bioconjugation strategies where temporary amine protection is required.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and insecticides with specific activity profiles.
• Material Science Research: Employed in the development of advanced polymers, dyes, and liquid crystals that require tailored aromatic amine components.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and inhibitors for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	Boc-2,4-Dimethylaniline
CAS No.	129822-43-1
Molecular Formula	C₁₃H₁₉NO₂
Molecular Weight	221.30 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-2,4-dimethylaniline; N-Boc-2,4-dimethylaniline; 2,4-Dimethylaniline N-Boc derivative; tert-Butyl (2,4-dimethylphenyl)carbamate; 1-(2,4-Dimethylphenyl)-2-(tert-butoxycarbonyl)amine; Boc-2,4-xylidine; N-(2,4-Dimethylphenyl)carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our Boc-2,4-Dimethylaniline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.