Description

Desacetyl Acetaminophen Glutathione is a specialized biochemical conjugate of a modified analgesic metabolite and the tripeptide glutathione. This compound is of significant interest in advanced pharmaceutical research and development, particularly for studying metabolic pathways and detoxification mechanisms. It serves as a critical intermediate or reference standard for scientists and manufacturers in the pharmaceutical, biotechnology, and nutraceutical sectors.

Application

• Pharmaceutical Intermediate: Used in the research and synthesis of novel analgesic or hepatoprotective drug candidates.
• Biochemical Research: Acts as a reference standard or probe for studying acetaminophen metabolism, glutathione conjugation pathways, and cellular detoxification processes.
• Metabolite Analysis: Serves as a critical analytical standard in LC-MS or HPLC methods for quantifying specific drug metabolites in pharmacokinetic studies.
• Nutraceutical Formulation R&D: Investigated for potential applications in advanced dietary supplements targeting liver health and antioxidant support.
• Toxicology Studies: Employed in research models to understand drug-induced liver injury and the protective role of glutathione systems.

Basic Information

Product Name	Desacetyl Acetaminophen Glutathione
CAS No.	129762-76-1
Molecular Formula	C16H21N3O7S
Molecular Weight	399.42 g/mol
Synonyms	N-(4-Hydroxyphenyl)glycinyl-S-glutathionylamide; 4'-Hydroxy-3-(glutathion-S-yl)acetanilide; APAP-GSH; Acetaminophen Glutathione Adduct; Paracetamol Glutathione Conjugate; N-Acetyl-p-benzoquinone imine-Glutathione Adduct (Reduced Form); Desacetyl Acetaminophen-GSH
EINECS	Contact for details

Quality Control

Our Desacetyl Acetaminophen Glutathione is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). We provide Certificates of Analysis (COA) with detailed batch-specific results to ensure traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.