Description

5-Aminolevulinic Acid-3-13C Hydrochloride is a stable, isotopically labeled hydrochloride salt form of the key biochemical precursor 5-aminolevulinic acid (5-ALA). This compound is essential for researchers and manufacturers requiring high-purity, stable-labeled materials for advanced analytical and diagnostic applications. It is primarily utilized in the pharmaceutical, life science, and clinical diagnostics sectors for metabolic pathway tracing, quantitative mass spectrometry, and the development of photodynamic therapy agents.

Application

• Stable Isotope-Labeled Internal Standard for the precise quantification of 5-ALA and related metabolites in biological matrices using LC-MS/MS.
• Metabolic Pathway Tracer in biochemical research to study the heme biosynthesis pathway and porphyrin metabolism.
• Precursor in Pharmaceutical Development for the synthesis of labeled prodrugs used in photodynamic therapy (PDT) for cancer treatment.
• Diagnostic Agent Research in the development of advanced clinical assays for porphyrias and other metabolic disorders.
• Biochemical Reagent in enzymatic studies and high-throughput screening assays targeting the ALA synthase pathway.

Basic Information

Product Name	5-Aminolevulinic Acid-3-13C Hydrochloride
CAS No.	129720-95-2
Molecular Formula	C4H8NO3Cl•13CH3
Molecular Weight	168.57 g/mol (for 13C labeled form)
Synonyms	5-ALA-3-13C Hydrochloride; δ-Aminolevulinic Acid-3-13C HCl; 5-Amino-4-oxopentanoic Acid-3-13C Hydrochloride; 13C-Labeled 5-ALA HCl; 5-Aminolaevulinic Acid-3-13C Hydrochloride; ALA-3-13C Hydrochloride; 5-Amino-4-oxovaleric Acid-3-13C Hydrochloride
EINECS	Contact for details

Quality Control

Our 5-Aminolevulinic Acid-3-13C Hydrochloride is manufactured under strict quality systems to ensure batch-to-batch consistency and high isotopic purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as chemical purity, isotopic enrichment, and impurity profile. We adhere to relevant industry guidelines for fine chemical and labeled compound production to meet the exacting standards of research and pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (MS)	≥ 99 atom % 13C
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.