Description

Galactosamine Hydrochloride, D-, [1-3H(N)] is a tritium-labeled derivative of D-galactosamine hydrochloride, a crucial amino sugar used in biochemical research. This radiolabeled compound is essential for conducting precise metabolic and pharmacokinetic tracer studies, enabling researchers to track pathways with high sensitivity. It is primarily utilized by scientists in the pharmaceutical, biotechnology, and academic research sectors for investigating glycosaminoglycan biosynthesis, liver metabolism, and carbohydrate-related disease mechanisms. The product is supplied with a specific activity suitable for advanced in vitro and in vivo applications.

Application

• Metabolic Tracer Studies: Used to trace and quantify the metabolic pathways of amino sugars in biological systems.
• Glycosaminoglycan (GAG) Research: Investigates the biosynthesis of chondroitin sulfate, keratan sulfate, and other GAGs.
• Hepatotoxicity Models: Serves as a tool in research models for studying drug-induced liver injury and metabolic disorders.
• Carbohydrate Chemistry & Biochemistry: Acts as a labeled precursor in enzymatic studies and glycoconjugate synthesis.
• Pharmaceutical R&D: Facilitates ADME (Absorption, Distribution, Metabolism, Excretion) studies for novel therapeutic agents targeting carbohydrate metabolism.
• Cell Biology & Signal Transduction: Used to study the role of galactosamine in cell surface receptor function and signaling pathways.

Basic Information

Product Name	Galactosamine Hydrochloride, D-, [1-3H(N)]
CAS No.	129521-69-3
Molecular Formula	C6H14ClNO5 (³H labeled)
Molecular Weight	~215.63 g/mol (unlabeled)
Synonyms	D-Galactosamine hydrochloride, tritiated; 2-Amino-2-deoxy-D-galactose hydrochloride (³H); (3H)GalN-HCl; GalN-HCl [1-³H]; 2-Deoxy-2-amino-D-galactopyranose hydrochloride (tritiated); Chondrosamine hydrochloride (³H); D-(+)-Galactosamine hydrochloride [1-³H(N)]; Tritium-labeled D-galactosamine HCl
EINECS	Contact for details

Quality Control

Every batch of our tritium-labeled Galactosamine Hydrochloride is manufactured and handled under strict quality protocols to ensure radiochemical purity and specific activity consistency. Our products undergo rigorous quality testing, including analytical HPLC and radiometric detection, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing specific activity, radiochemical purity, chemical purity, and solvent composition is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at or below -20°C. Due to its hygroscopic (moisture-sensitive) nature, the product should be handled in a controlled, dry environment. For long-term stability, store in a dedicated freezer for radioactive materials. Follow all applicable local and international regulations for the storage and handling of radioactive compounds.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Specific Activity	10-40 Ci/mmol (Contact for exact value)
Radiochemical Purity (HPLC)	≥ 95%
Chemical Purity (HPLC)	≥ 98%
Solvent (for solutions)	Ethanol:Water (Specified ratio)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.