Description

Bis(Msh)-Dtpa CAS NO 129494-00-4 is a specialized chelating agent and functional intermediate, recognized for its unique molecular structure that incorporates multiple coordination sites. This compound is critical for applications requiring precise metal ion binding and controlled reactivity, offering superior performance in complex chemical formulations. It is primarily utilized by manufacturers in the pharmaceutical, advanced material science, and specialty chemical synthesis sectors.

Application

• Pharmaceutical Intermediate: Used in the synthesis of advanced drug candidates, particularly those requiring metal-chelating moieties for therapeutic activity or diagnostic imaging.
• Radiopharmaceuticals: Serves as a bifunctional chelator for labeling biomolecules with radioactive isotopes for targeted cancer therapy and diagnostic imaging (e.g., PET, SPECT).
• Contrast Agent Precursor: A key building block in the production of gadolinium-based and other lanthanide contrast agents for Magnetic Resonance Imaging (MRI).
• Catalyst Ligand: Functions as a ligand in homogeneous catalysis for various organic transformations, enhancing selectivity and yield.
• Polymer Modification: Incorporated into polymer chains to introduce metal-binding functionality for creating smart materials, sensors, or water treatment resins.
• Analytical Chemistry: Employed as a complexing agent in analytical methods for the separation, detection, or quantification of specific metal ions.
• Research & Development: A valuable tool in chemical and biochemical research for studying metal-protein interactions and developing new chelation therapies.

Basic Information

Product Name	Bis(Msh)-Dtpa
CAS No.	129494-00-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	2,2',2'',2'''-(2-(4-((2-Mercaptoethyl)thio)-1,4,7-triazacyclononane-1,4,7-triyl)diacetate(5-))tetraacetic acid; MSH-DTPA; DTPA-bis(mercaptoethylamide); Bifunctional DTPA derivative; DTPA-bis(amide-thiol); 1,4,7-Triazacyclononane-N,N',N''-triacetic acid, 2-(4-((2-mercaptoethyl)thio)-; Chelator for radiolabeling
EINECS	Contact for details

Quality Control

Our Bis(Msh)-Dtpa is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for pharmaceutical and research applications. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.