Description

Pyroglutamyl-Glutamyl-Glycyl-Seryl-Asparagine is a synthetic peptide sequence of significant interest in biochemical research and pharmaceutical development. This compound is valued for its role as a building block in peptide synthesis and as a model substrate for studying enzymatic activity and protein-protein interactions. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in proteomics, drug discovery, and the development of novel therapeutic agents.

Application

• Biochemical Research: Used as a standard or substrate in enzymatic assays and proteomics studies to investigate protease specificity and kinetics.
• Pharmaceutical R&D: Serves as a key intermediate or reference compound in the discovery and development of peptide-based therapeutics and diagnostic tools.
• Peptide Synthesis: Acts as a crucial building block for the solid-phase or solution-phase synthesis of longer, more complex peptide chains.
• Cell Culture & Signaling Studies: Employed in studies exploring cellular signaling pathways and receptor-ligand interactions due to its specific sequence.
• Antibody Production: Can be used as a hapten or immunogen for generating sequence-specific antibodies for immunological assays.
• Quality Control Standards: Functions as a high-purity reference standard for analytical method development and validation in QC laboratories.

Basic Information

Product Name	Pyroglutamyl-Glutamyl-Glycyl-Seryl-Asparagine
CAS No.	129276-54-6
Molecular Formula	C19H28N6O11
Molecular Weight	516.46 g/mol
Synonyms	pGlu-Glu-Gly-Ser-Asn; Pyroglutamic Acid-Glutamic Acid-Glycine-Serine-Asparagine; 5-Oxoprolyl-glutamyl-glycyl-seryl-asparagine; L-Pyroglutamyl-L-glutamyl-glycyl-L-seryl-L-asparagine; pGlu-E-G-S-N; pGlu-Glu-Gly-Ser-Asn-OH; Pyr-Glu-Gly-Ser-Asn; Glp-Glu-Gly-Ser-Asn
EINECS	Contact for details

Quality Control

Our Pyroglutamyl-Glutamyl-Glycyl-Seryl-Asparagine is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to rigorous internal quality standards and can provide material tailored to specific project requirements, including research-grade and GMP-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.