Description

Perospirone Hydrochloride is a high-purity active pharmaceutical ingredient (API) belonging to the atypical antipsychotic class. It is a critical intermediate and reference standard in the research, development, and quality control of neuropsychiatric medications. This compound is essential for pharmaceutical manufacturers, analytical laboratories, and R&D institutions focused on central nervous system (CNS) therapeutics.

Application

• Pharmaceutical Active Ingredient (API): Primary use as the key active component in the formulation of antipsychotic medications.
• Reference Standard: Serves as a certified standard for analytical methods, including HPLC, LC-MS, and NMR, to ensure product quality and regulatory compliance.
• Research & Development: Used in preclinical and clinical studies to investigate mechanisms of action, pharmacokinetics, and new therapeutic applications for schizophrenia and related disorders.
• Process Development & Scale-up: Employed as a benchmark in the optimization and validation of synthetic routes for commercial manufacturing.
• Impurity Profiling: Critical for identifying, characterizing, and quantifying related substances and degradation products in drug substances and products.
• Regulatory Submissions: Provides essential data for Drug Master Files (DMFs), Investigational New Drug (IND) applications, and New Drug Applications (NDAs).

Basic Information

Product Name	Perospirone Hydrochloride
CAS No.	129273-38-7
Molecular Formula	C23H30N4O2S · HCl
Molecular Weight	463.04 g/mol
Synonyms	Perospirone HCl; SM-9018; (3aR,4S,7R,7aS)-2-[(4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]butyl]hexahydro-4,7-methano-1H-isoindole-1,3(2H)-dione Hydrochloride; Lullan (brand name); 1-{4-[4-(1,2-Benzothiazol-3-yl)piperazin-1-yl]butyl}-3a,4,7,7a-tetrahydrospiro[isoindole-2(1H),2'-[1,3]dioxolan]-1,3-dione Hydrochloride
EINECS	Contact for details

Quality Control

Our Perospirone Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for identity, purity, and potency, aligning with ICH guidelines. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5% Any single impurity ≤0.5%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.