Description

(5-Aminopentyl)(Phenylmethoxy)Carbamic Acid tert-Butyl Ester is a protected amino acid derivative, specifically a Boc-protected amine with a benzyloxy side chain, serving as a critical building block in organic synthesis. Its primary value lies in providing a versatile, orthogonal protecting group strategy for the synthesis of complex peptides and other bioactive molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who require high-purity intermediates for drug discovery and development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of peptide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to introduce a protected lysine or ornithine-like side chain.
• Protecting Group Chemistry: The tert-butyloxycarbonyl (Boc) group provides acid-labile protection for amines, enabling sequential deprotection strategies in multi-step syntheses.
• Bioconjugation: Serves as a linker or spacer molecule in the development of antibody-drug conjugates (ADCs) and other bioconjugates.
• Chemical Biology Probes: Utilized in the creation of labeled peptides and molecular probes for biochemical and cellular studies.
• Custom Synthesis: A valuable starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke organic compounds.

Basic Information

Product Name	(5-Aminopentyl)(Phenylmethoxy)Carbamic Acid tert-Butyl Ester
CAS No.	129245-21-2
Molecular Formula	C₁₇H₂₈N₂O₃
Molecular Weight	308.42 g/mol
Synonyms	N-Boc-N'-(5-aminopentyl)-O-benzyl-L-serinamide; tert-Butyl N-[5-[[(benzyloxy)carbonyl]amino]pentyl]carbamate; 5-[[(Benzyloxy)carbonyl]amino]-1-[[(1,1-dimethylethoxy)carbonyl]amino]pentane; Boc-NH-(CH2)5-NH-Cbz; Nα-Boc-Nε-Cbz-L-lysine derivative; N-Boc-1,5-diaminopentane N-Cbz derivative
EINECS	Contact for details

Quality Control

Our (5-Aminopentyl)(Phenylmethoxy)Carbamic Acid tert-Butyl Ester is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are provided with every shipment. We support compliance with cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.