Description

2-(α-Fluoroethyl)Tetrahydrobenzimidazole CAS NO 129238-73-9 is a specialized fluorinated heterocyclic compound that serves as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity imparted by the fluoroethyl group, enabling precise molecular modifications. This intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used to construct advanced fungicides and herbicides with enhanced efficacy and environmental profiles.
• Ligand and Catalyst Development: Serves as a backbone for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of fluorinated polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis Projects: A versatile starting material for contract research organizations (CROs) and fine chemical manufacturers.

Basic Information

Product Name	2-(α-Fluoroethyl)Tetrahydrobenzimidazole
CAS No.	129238-73-9
Molecular Formula	C9H15FN2
Molecular Weight	170.23 g/mol
Synonyms	2-(1-Fluoroethyl)-4,5,6,7-tetrahydro-1H-benzimidazole; 2-(1-Fluoroethyl)-1H-benzimidazole, 4,5,6,7-tetrahydro-; 2-(α-Fluoroethyl)tetrahydrobenzimidazole; 2-(1-Fluoroethyl)-4,5,6,7-tetrahydrobenzimidazole; Tetrahydro-2-(1-fluoroethyl)benzimidazole; 129238-73-9; 2-(1-Fluoroethyl)-4,5,6,7-tetrahydro-1H-benzo[d]imidazole
EINECS	Contact for details

Quality Control

Our production of 2-(α-Fluoroethyl)Tetrahydrobenzimidazole adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all critical specifications. We support compliance with cGMP and ISO 9001 standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorinating agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.