Description

(R)-(-)-o-Anisylmethylphenylphosphine Borane is a chiral phosphine borane complex, a valuable precursor to air-sensitive tertiary phosphine ligands. This compound is significant for its role as a stable, storable source of chiral phosphines, which are crucial catalysts in asymmetric synthesis. It is primarily needed by research and development laboratories and production facilities in the pharmaceutical and fine chemical industries for the development of novel active pharmaceutical ingredients (APIs) and high-value chiral intermediates.

Application

• Asymmetric Catalysis: As a key ligand precursor for transition metal catalysts used in asymmetric hydrogenation, cross-coupling, and other stereoselective transformations.
• Pharmaceutical Intermediate Synthesis: For the production of enantiomerically pure drug candidates and active pharmaceutical ingredients (APIs).
• Chiral Auxiliary Development: In the research and development of new chiral ligands and organocatalysts.
• Fine Chemical Manufacturing: For the synthesis of complex, high-value specialty chemicals requiring precise stereochemical control.
• Academic and Industrial R&D: As a critical reagent in methodological studies and process development for asymmetric synthesis.

Basic Information

Product Name	(R)-(-)-o-Anisylmethylphenylphosphine Borane
CAS No.	129212-59-5
Molecular Formula	C15H20BOP
Molecular Weight	258.10 g/mol
Synonyms	(R)-(-)-o-Methoxyphenylmethylphenylphosphine Borane; (R)-(-)-o-Anisylmethylphenylphosphine-Borane Complex; (R)-o-Anisylmethylphenylphosphine Borane Adduct; (R)-Methyl(o-methoxyphenyl)phenylphosphine Borane; (R)-(-)-MOP-Borane; (R)-(-)-o-Anisylmethylphenylphosphine BH3; (R)-(-)-o-Anisylmethylphenylphosphine Borane Adduct; (R)-(-)-Methyl(2-methoxyphenyl)phenylphosphine Borane
EINECS	Contact for details

Quality Control

Our (R)-(-)-o-Anisylmethylphenylphosphine Borane is manufactured under strict quality control protocols to ensure high chemical purity and enantiomeric excess, critical for reproducible results in sensitive asymmetric syntheses. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and identity confirmation. We adhere to cGMP standards where applicable to support pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.