Description

Dansyl Myelin Basic Protein, Gly(119)-Gly(131)- CAS NO 129189-42-0 is a synthetic, dansyl-labeled peptide fragment corresponding to a specific epitope of myelin basic protein (MBP). This compound is a critical research tool for studying demyelinating diseases, such as multiple sclerosis, and for immunological assay development. It is primarily utilized by researchers and diagnostic manufacturers in the fields of neuroscience, immunology, and autoimmune disease diagnostics.

Application

• Biomarker Research: Key reagent for investigating the role of MBP epitopes in the pathogenesis of multiple sclerosis and other demyelinating disorders.
• Immunoassay Development: Used as a labeled antigen in the development and calibration of ELISA and other immunoassays to detect anti-MBP antibodies.
• T-Cell Epitope Mapping: Essential for studying T-cell recognition and activation specific to the Gly(119)-Gly(131) sequence of MBP.
• Fluorescence-Based Studies: The dansyl fluorophore enables its use in fluorescence polarization (FP), FRET, and other fluorescence detection methodologies.
• Quality Control Standard: Serves as a reference standard in the production and validation of diagnostic kits for autoimmune neurological conditions.
• Academic & Pharmaceutical R&D: Supports basic research and drug discovery programs targeting myelin and autoimmune responses.

Basic Information

Product Name	Dansyl Myelin Basic Protein, Gly(119)-Gly(131)- CAS NO 129189-42-0
CAS No.	129189-42-0
Molecular Formula	C84H130N24O24S2
Molecular Weight	1891.2 g/mol (theoretical)
Synonyms	Dansyl-MBP(119-131); Glycyl-dansyl MBP fragment 119-131; 5-(Dimethylamino)naphthalene-1-sulfonyl-MBP(119-131); MBP epitope (119-131), dansylated; Dansyl-labeled myelin basic protein peptide; Autoantigen peptide; MBP Gly119-Gly131 dansyl conjugate; Diagnostic research peptide
EINECS	Contact for details

Quality Control

Every batch of Dansyl Myelin Basic Protein, Gly(119)-Gly(131)- CAS NO 129189-42-0 is manufactured under strict quality protocols. Our products undergo rigorous quality testing, including HPLC for purity and MS for identity confirmation, to ensure compliance with research-grade standards. Certificates of Analysis (COA) detailing purity, peptide content, and analytical data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, keep desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.